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Biological membranes are not a simple homogeneous layer of proteins and lipids, but rather are organized into discrete regions that can be characterized by distinct lipid and protein content. These membrane microdomains which have been named “lipid rafts, are mainly composed of sphingolipids packed together with sterols and play an … Continue reading →

Many essential, highly studied proteins are glycoproteins, which contain branched chains of sugar molecules (glycans) covalently attached at specific glycosylation sites. The attributes of the glycosylation of a protein can potentially affect the protein’s structure, stability, catalytic activity, and clearance rate. Currently, there is a limited characterization of the relationship … Continue reading →